These activities fall within the scope of interventional radiology, a booming discipline, for which France ranks in the forefront in the world. The possibility of depositing an energy locally and non-invasively opens new perspectives for more reliable therapeutic strategies of malignant tumors, less aggressive for the patients, which will allow a reduction of time and costs of hospitalization. In this context, an activity of the IOP team is oriented around image processing methods in real time, allowing the guiding imaging (ultrasound or MRI) of a mini or non-invasive treatment (thermal ablation or radiotherapy), also allowing local deposition of medications.